“We can’t tell you the origin of the experience. But we can tell you the brain does appear to be built to have these [mystical] experiences. There are examples of people reaching similar states, spontaneously. But for the most part, it takes work. Meditation and these powerful prayer experiences require dedication and practice. But people have figured out how to do this, and the question is, ‘What is the source of that experience?’ The answer is, ‘We don’t know.’ Science doesn’t really have an answer for you.” ― Andrew B. Newberg, Fringe-ology: How I Tried to Explain Away the Unexplainable-And Couldn’t

“Meditation has also been proven scientifically to untangle and rewire the neurological pathways in the brain that make up the conditioned personality. Buddhist monks, for example, have had their brains scanned by scientists as they sat still in deep altered states of consciousness invoked by transcendental meditation and the scientists were amazed at what they beheld. The frontal lobes of the monks lit up as bright as the sun! They were in states of peace and happiness the scientists had never seen before. Meditation invokes that which is known in neuroscience as neuroplasticity; which is the loosening of the old nerve cells or hardwiring in the brain, to make space for the new to emerge. Meditation, in this sense, is a fire that burns away the old or conditioned self, in the Bhagavad Gita, this is known as the Yajna;“All karma or effects of actions are completely burned away from the liberated being who, free from attachment, with his physical mind enveloped in wisdom (the higher self), performs the true spiritual fire rite.” ― Craig Krishna, The Labyrinth: Rewiring the Nodes in the Maze of your Mind